stem cell expansion and controlled tissue genesis

2. 연사 : Justin J. Cooper-White Ph.D.

            Professor, The University of Queensland

3. 일시 : 2011년 9월 19일 (월) 4:30PM-5:30PM

4. 장소 : 301동 1512-2호 세미나실

 

5. 내용 : Innovations in microfabrication and nanofabrication over the past decade have paved the way for the development of a plethora of microfluidic and nanofluidic devices, in which the fluidic length scales typically range from 100’s of microns to 10’s of nanometers. These advances in microfabrication have permitted the development of synthetic microenvironments for cell culture, designed to better represent the in vivo cellular microenvironments, at least in terms of mass, momentum and heat transport lengthscales (10’s – 100’s microns).  These devices are proving to be very useful in screening microenvironmental cues (e.g. soluble factors, small molecules, ligands, oxygen) for optimum stem cell culture and expansion and tissue genesis of a multitude of tissues, including blood vessels, heart muscle, cartilage and bone. In this presentation I will detail the development of a number of cell-based diagnostic microdevices and microbioreactor platforms for human pluripotent stem cell expansion and small molecule screening, cell migration and space colonisation and ex vivo vascular pedicle development, including the associated novel insights that such devices can provide. A brief overview of my laboratories activities in the areas of advanced biomaterials and tissue engineering will also be provided.

 

 

6. 약력 : Professor Justin Cooper-White has research interests in biomaterials processing, tissue engineering, non-Newtonian fluid mechanics, rheology and microfluidics. The Tissue Engineering and Microfluidics (TEAM) Laboratory has projects in all of these areas with a common focus of providing fundamental insight into complex polymer-based structures and systems, with the aim of ultimately tailoring and controlling their interactions with biological systems. In detail, these projects are investigating novel methods of manufacturing polymeric scaffolds and methods of surface engineering of these scaffolds for drug delivery and tissue engineering applications, new in vitro modules for mapping cell-surface and cell-scaffold interactions, manufacturing functional microparticles with micro processing plants and complex fluid behaviour in microdevices.

 

※ 문의 : 기계항공공학부  전누리 교수 (880-7111)