WCU seminar

1.제목 : Vascularizing Engineered Tissues In Vitro

2.연사 : Professor Steven C. George (University of California, Irvine)

3.일시 : 2013년 6월 27일(목) 오후 4:00 – 6:00시 

4.장소 : 301동 1512-2호

5.내용 : 

 Tissue engineering holds enormous potential to not only replace or restore function to a wide range of tissues, but also to capture and control three-dimensional physiology in vitro (e.g., microphysiological systems).  The latter has important applications in the fields of drug development, toxicity screening, modeling tumor metastasis, and repairing damaged cardiac (heart) muscle. In order to replicate the complex 3-D arrangement of cells and extracellular matrix (ECM), new human microphysiological systems must be developed, and must include a vascular supply.  The vasculature not only provides the necessary convective transport of nutrients and waste in 3-D culture, it also couples and integrates the response of multiple organ systems.  The past decade has brought tremendous advances in our understanding of new blood vessel formation, providing a rich environment to vascularize engineered tissues.  Over the past two years we have developed a novel microfluidic-based system of 3-D human microtissues (~ 1 mm³) perfused with a network of human microvessels.  This seminar will describe our approach and early results, including applications in tumor biology and cardiac tissue.

6. 약력:

Dr. George received his bachelors degree in chemical engineering in 1987 from Northwestern University, M.D. from the University of Missouri School of Medicine in 1991, and  Ph.D. from the University of Washington in chemical engineering in 1995.  He then joined the faculty at the University of California, Irvine.  His research interests include tissue engineering with particular interest in vascularizing engineered tissues, and linking optical and mechanical properties of tissue.  His research program is currently supported by four grants from the National Institutes of Health including his role as the PI on a new T32 training grant in cardiovascular technology and entrepreneurship.  The NIH FIRST award in 1998 and the CAREER and Presidential Early Career Award for Scientists and Engineers (PECASE) from the National Science Foundation in 1999 have previously recognized his work.  He became the Director of the Center for Biomedical Engineering in October 2000, and served as the Principal Investigator of the Development Award from the Whitaker Foundation from 2000-2006. He was elected a fellow in the American Institute of Medical and Biological Engineering (AIMBE) in 2007, and has published more than 90 peer-reviewed manuscripts.  He was the founding William J. Link Professor and Chair of the Department of Biomedical Engineering at UCI from 2002-2009, and has served as the founding Edwards Lifesciences Professor and Director of The Edwards Lifesciences Center for Advanced Cardiovascular Technology since 2009.

7. 문의:  기계항공공학부 전누리 교수 (880-7111)